Occurrence of 2-hydroxy fatty acids in animal tissues

Occurrence of 2-hydroxy Fatty Acids in Animal Tissues.

Fatty Acids: Hydroxy and Other Oxygenated Structures, Occurrence and Biochemistry

The following is a guide to the more important naturally occurring fatty acids with hydroxy, epoxy (furanoid), methoxy and oxo substituents, but it is not intended to be a comprehensive list. The prostaglandins and other eicosanoids and the plant oxylipins are in essence fatty acids with additional oxygenated functional groups, but these are discussed elsewhere in this website. Similarly, hydro...

Distribution of 3-hydroxy fatty acids in tissues after intraperitoneal injection of endotoxin.

BACKGROUND 3-Hydroxy fatty acids (3-OH FAs) with 10- to 18-carbon chain lengths are constituents of the endotoxin [lipopolysaccharide (LPS)] of gram-negative bacteria. We investigated whether these FAs may be used as chemical markers in measuring endotoxin concentrations in mammalian tissue samples. METHODS We used gas-liquid chromatography-tandem mass spectrometry to measure 3-OH FAs in seru...

Determination of nucleic acids in animal tissues.

As reported in a previous paper (l), a new microchemical method for the determination of deoxyribonucleic acid (DNA) has been devised which permits the evaluation of DNA in amounts as small as 2.5 y per ml. The method is particularly useful with very small quantities of tissue. For this reason a study was undertaken to learn the best conditions for the application of the method to the determina...

The metabolism and availability of essential fatty acids in animal and human tissues.

Essential fatty acids (EFA), which are not synthesized in animal and human tissues, belong to the n-6 and n-3 families of polyunsaturated fatty acids (PUFA), derived from linoleic acid (LA, 18:2n-6) and alpha-linolenic acid (LNA, 18:3n-3). Optimal requirements are 3-6% of ingested energy for LA and 0.5-1% for LNA in adults. Requirements in LNA are higher in development. Dietary sources of LA an...